Ma, J., Bi, L., Spurlin, J., and Lwigale P. (2022). Nephronectin-Integrin a8 signaling is required for proper migration of periocular neural crest cells during chick corneal development. eLife 2022;11:e74307DOI: 7554/eLife.74307
Koudouna, E., Spurlin, J., Babushkina, A. et al. Recapitulation of normal collagen architecture in embryonic wounded corneas. Sci Rep 10, 13815 (2020). https://doi.org/10.1038/s41598-020-70658-y
Young RD, Knupp C, Koudouna E, Ralphs JR, Ma Y, Lwigale PY, et al. Observations on nascent matrix structures in embryonic cornea: Important in cell interactions, or merely vestiges of the lens surface? Arch Clin Exp Ophthalmol 2020; 2(2):67-72.
Babushkina, A., Lwigale, P., Periocular neural crest cell differentiation into corneal endothelium is influenced by signals in the nascent corneal environment, Developmental Biology, https://doi.org/10.1016/j.ydbio.2020.06.012
Portal C, Rompolas P, Lwigale P, Iomini C. (2019) Primary cilia deficiency in neural crest cells models anterior segment dysgenesis in mouse. Elife. PMID: 31845891
Young RD, Knupp C, Koudouna E, Ralphs JR, Ma Y, Lwigale PY, Jester JV, Quantock AJ. (2019) Cell-independent matrix configuration in early corneal development. Experimental Eye Research. PMID: 31445001.
Bi L, Lwigale P. (2019) A Transcriptomic Analysis of Differential Gene Expression during Chick Periocular Neural Crest Differentiation into Corneal Cells. Developmental Dynamics. PMID: 31004457.
Cui R, Lwigale P. (2019) Expression of the heparin-binding growth factors Midkine and
pleiotrophin during ocular development. Gene Expression Patterns. 27;32:28-37. PMID: 30825522.
Ma J, Lwigale P.(2019) Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea.
Investigative Ophthalmology & Visual Science; 60(2):661-676. PMID: 30786278
Ojeda AF, Munjaal RP, Lwigale PY.(2017) Knockdown of CXCL14 disrupts neurovascular patterning during ocular development. Developmental Biology, 423(1):77-91.
Kwiatkowski, SC., Ojeda, AF., and Lwigale PY (2016) “PlexinD1 is required for Vascular Patterning in the periocular region and Establishment of Corneal Avascularity.” Developmental Biology, 411: 128-139.
Agrawal SJ and Lwigale PY. Quail-chick chimeras and eye development. Methods Mol Biol. (2015) 1189:255-263
Lwigale, P.Y. Corneal Development: Different Cells from a Common Progenitor. Prog Mol Biol Transl Sci. 2015;134:43-59. Doi:10.1016/bs.pmbts.2015.04.003. Jun 4.
Chelsey C. McKenna, Ana Ojeda, James W Spurlin, Sam Kwiatkowski and Peter Lwigale. Sema3A maintains corneal avascularity during development by inhibiting Vegf induced angioblast migration. Dev Biol. 2014 Jul 15;391(2):241-50. doi: 10.1016/j.ydbio.2014.04.017.
James W Spurlin, III and Peter Lwigale. Wounded Embryonic Corneas Exhibit Non-fibrotic Regeneration and Complete Innervation. Invest. Ophthalmol. Vis. Sci. September 3, 2013, 54: 6334-6344
Jennifer R. Chao, Marianne E. Bronner, and Peter Y. Lwigale. Human fetal keratocytes have multipotent characteristics in the developing avian embryo. Stem Cells and Development. August 1, 2013, 22(15): 2186-2195. doi:10.1089/scd.2013.0011.
Ana Ojeda, Ravi P. Munjaal, Peter Y. Lwigale. Expression of CXCL12 and CXCL14 during eye development in Chick and Mouse.Gene expression patterns, 2013
Sam Kwiatkowski, Ravi P. Munjaal, Teresa Lee, Peter Y. Lwigale. Expression of pro- and anti-angiogenic factors during the formation of the periocular vasculature and development of the avian cornea. Dev. Dynamics. 2013 DOI: 10.1002/dvdy.23956
James Spurlin and Peter Lwigale. A technique to increase accessibility to late-stage chick embryos for in ovo manipulations. Developmental Dynamics. 2012 DOI:10.1002/dvdy.23907
Chelsey C. McKenna, Ravi P. Munjaal, Peter Y. Lwigale. Distinct Roles for Neuropilin1 and Neuropilin2 during Mouse Corneal Innervation. PLoS ONE. 2012 7(5): e37175. doi:10.1371/journal.pone.0037175
Griswold SL, Lwigale PY. Analysis of Neural Crest Migration and Differentiation by Cross-species Transplantation. Journal of Vis Exp. Epub 2012 Feb 7. link to videopii: 3622. doi: 10.3791/3622. PMID: 22349214
Schwend T, Lwigale PY, Conrad GW. Nerve repulsion by the lens and cornea during cornea innervation is dependent on Robo-Slit signaling and diminishes with neuron age. Dev Biol. 2012 Mar 1;363(1):115-27. Epub 2012 Jan 3. PMID: 22236962
McKenna CC, Lwigale PY. Innervation of the mouse cornea during development. Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):30-5. Print 2011 Jan. PubMed PMID: 20811061; PubMed Central PMCID: PMC3053279.
–Before 2010–
Lwigale PY, Bronner-Fraser M. Semaphorin3A/neuropilin-1 signaling acts as a
molecular switch regulating neural crest migration during cornea development. Dev
Biol. 2009 Dec 15;336(2):257-65. Epub 2009 Oct 13. PubMed PMID: 19833121; PubMed
Central PMCID: PMC2800376.
Lee VM, Lwigale PY. Neural crest, sensory neuron, and muscle cultures. Methods
Cell Biol. 2008;87:115-33. Review. PubMed PMID: 18485294.
Lwigale PY, Schneider RA. Other chimeras: quail-duck and mouse-chick. Methods
Cell Biol. 2008;87:59-74. Review. PubMed PMID: 18485291.
Shiau CE, Lwigale PY, Das RM, Wilson SA, Bronner-Fraser M. Robo2-Slit1
dependent cell-cell interactions mediate assembly of the trigeminal ganglion. Nat
Neurosci. 2008 Mar;11(3):269-76. Epub 2008 Feb 17. PubMed PMID: 18278043.
Lwigale PY, Bronner-Fraser M. Lens-derived Semaphorin3A regulates sensory
innervation of the cornea. Dev Biol. 2007 Jun 15;306(2):750-9. Epub 2007 Apr 18.
PubMed PMID: 17499699.
Lwigale PY, Cressy PA, Bronner-Fraser M. Corneal keratocytes retain neural
crest progenitor cell properties. Dev Biol. 2005 Dec 1;288(1):284-93. Epub 2005
Nov 2. PubMed PMID: 16263107.
Cerny R, Lwigale P, Ericsson R, Meulemans D, Epperlein HH, Bronner-Fraser M.
Developmental origins and evolution of jaws: new interpretation of “maxillary”
and “mandibular”. Dev Biol. 2004 Dec 1;276(1):225-36. PubMed PMID: 15531376.
Lwigale PY, Conrad GW, Bronner-Fraser M. Graded potential of neural crest to
form cornea, sensory neurons and cartilage along the rostrocaudal axis.
Development. 2004 May;131(9):1979-91. Epub 2004 Mar 31. PubMed PMID: 15056619.
Lwigale PY. Embryonic origin of avian corneal sensory nerves. Dev Biol. 2001
Nov 15;239(2):323-37. PubMed PMID: 11784038.
Riley NC, Lwigale PY, Conrad GW. Specificity of corneal nerve positions
during embryogenesis. Mol Vis. 2001 Dec 21;7:297-304. PubMed PMID: 11754335.
Lwigale PY, Thurmond JE, Norton WN, Spooner BS, Wiens DJ. Simulated
microgravity and hypergravity attenuate heart tissue development in explant
culture. Cells Tissues Organs. 2000;167(2-3):171-83. PubMed PMID: 10971041.
Lwigale PY. Nuclear morphologies of bovine corneal cells as visualized by
confocal microscopy. Cells Tissues Organs. 1999;165(2):104-12. PubMed PMID:
10516423.